
Latest Science News
IRBM Discovers Potent Allosteric Inhibitor for Zika Virus
IRBM announced a breakthrough with a novel allosteric inhibitor targeting the Zika virus NS2B-NS3 protease, showing efficacy in preclinical models and potential against other flaviviruses like dengue. The molecule suppresses viral replication with a favorable safety profile, developed via integrated screening and chemistry.
Published in Nature Communications, this addresses the lack of approved ZIKV treatments.
Tumors Reprogram Neutrophils to Fuel Cancer Growth
University of Geneva researchers found tumors reprogram neutrophils, immune defenders, to promote cancer instead of fighting it. This surprising mechanism turns the immune system to the tumor's advantage.
The discovery highlights new targets for immunotherapy.
NIH Creates Digital Twin of Eye Cells for AMD Research
NIH scientists developed the first subcellular resolution digital twin of retinal pigment epithelial cells using AI-driven POLARIS to study age-related macular degeneration. It reveals how cells lose polarity in AMD, aiding therapeutic discovery.
The model tracks cell organization from healthy to diseased states.
Genetically Engineered Wax Moths to Replace Mice in AMR Research
University of Exeter created the world's first genetically engineered wax moths for infection research, accelerating antimicrobial resistance studies ethically. These moths glow when infected, reducing mammal use by potentially sparing 10,000 mice yearly in the UK.
Published in Nature Lab Animal, enabling real-time biosensors.
Climate Models Miss Key Role of Plankton in Carbon Sequestration
New research shows tiny calcium carbonate-building marine plankton play an outsized role in pulling carbon to deep ocean, overlooked in climate models. These microbes regulate Earth's climate more than previously thought.
Urgent for accurate predictions.
Fossils in Algeria Rocks Suggest Life on Mars Possible
Using Lims mass spectrometer, scientists identified fossilized sulfur-oxidizing bacteria in Algeria rocks similar to Martian ones, with dolomite supporting organic origins. This bolsters hypotheses for ancient microbial life on Mars.
Developed for rover missions.
$4M Grants for Novel Brain Tumor Therapies
The Mark and Sontag Foundations awarded $4M for brain tumor research, including ASOs for glioblastoma immunotherapies and projects by Daniel Schramek and Jason Moffat. Aims to propel innovative treatments for aggressive cancers.
Four ASPIRE Awards of $250K each.